Making transgene dominant

  1. Can we make transgene dominant in the genetically engineered organism so that when it mates the offspring would have the same characteristics?
     
  2. jcsd
  3. Yes by insertion of the transgene in the germ cell
     
  4. Ygggdrasil

    Ygggdrasil 1,519
    Science Advisor

    Whether an allele of a gene acts in a dominant or recessive manner depends on the biochemistry of how the allele functions. In general, most loss-of-function alleles act in a recessive manner and most gain-of-function allele act in a dominant manner. Of course, there are many exceptions, such as dominant negative alleles which can interfere with the function of the wild type allele.

    Here's a previous PF thread on the topic:
    https://www.physicsforums.com/showthread.php?t=568436

    And here's a useful article on the subject:
    http://genetics.thetech.org/ask/ask227
     
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