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Making transgene dominant

  1. Dec 6, 2013 #1
    Can we make transgene dominant in the genetically engineered organism so that when it mates the offspring would have the same characteristics?
  2. jcsd
  3. Dec 6, 2013 #2
    Yes by insertion of the transgene in the germ cell
  4. Dec 6, 2013 #3


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    Whether an allele of a gene acts in a dominant or recessive manner depends on the biochemistry of how the allele functions. In general, most loss-of-function alleles act in a recessive manner and most gain-of-function allele act in a dominant manner. Of course, there are many exceptions, such as dominant negative alleles which can interfere with the function of the wild type allele.

    Here's a previous PF thread on the topic:

    And here's a useful article on the subject:
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