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Molecular genetics

  1. Jan 2, 2014 #1
    A portion of an mRNA molecule has the sequence CCUAGGCUA. What is the sequence of the anti sense strand of the corresponding DNA molecule?

    The anti sense strand is the coding strand. The 3' to 5' strand from which mRNA builds. Does that mean the sequence would be backwards?
     
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  3. Jan 3, 2014 #2

    epenguin

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    First part: write out your reasoning for thinking that.

    2nd part: are all bases the same in RNA and DNA?
     
  4. Jan 3, 2014 #3
    RNA has uracil instead of thymine

    So it would the complementary base pairs : GGATCCGAT?
     
  5. Jan 3, 2014 #4

    epenguin

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    Right.

    are you unsure? This is not for a guess, just a test of knowing how mRNA is synthesised, and the conventions. Do a little picture if nec and don't be afraid to attach 3' and 5' signs to your strand ends.
     
  6. Jan 3, 2014 #5
    Just to clarify if the question said sense strand instead of anti , it would be the same sequence given except it would have thymine instead of uracil right?
     
  7. Jan 8, 2014 #6

    epenguin

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    Is that the sequence complementary to the mRNA?

    yes I think that's a correct deduction.
     
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