Molecular Weight for nucleotides

In summary, daltons refer to atomic mass and (g/M) stands for gram per mole. Molecular Weight is the mass of 1 mole of a particular molecule, and by definition, 1 mole of carbon atoms weighs 12 grams. The number of grams that go into a mole is also known as a dalton. The reason why carbon is used as a reference and has a mass of exactly 12 is because it was easy to purify.
  • #1
mountain
53
0
When it says; "Molecular Weight: daltons (g/M)" What does daltons mean and what does (g/M) stand for? Does g/M stand for g/mol or what?

How can they calculate Molecular Weight for nucleotides?


Thanks for any inputs.
 
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  • #2
A dalton is an atomic mass. For instance C12 has a mass of 12.0000 Da. The mw is the mass of 1 mole of a particular molecule. By definition 1 mole of carbon atoms weighs 12 grams.
 
  • #3
Thanks.

But what does M stand for in g/M?
 
  • #4
mountain said:
Thanks.

But what does M stand for in g/M?

You had it right...mole.
 
  • #5
Monique said:
A dalton is an atomic mass. For instance C12 has a mass of 12.0000 Da. The mw is the mass of 1 mole of a particular molecule. By definition 1 mole of carbon atoms weighs 12 grams.
(why only four zeros?)

(1) C12 has a mass of 12 Da (by definition; exactly 12, there is no uncertainty)
(2) a mol of C12 atoms weighs 12 grams (by definition)

From (1) and (2) it follows that a dalton is the number of grams that go into a mol (gram/mol)
__________________________________________________
(1) C12 = 12 Da <--> mol C12 = mol 12 Da
(2) mol C12 = 12 gram
(substitute 2 into 1) 12 gram = mol 12 Da <--> gram/mol = Da
 
  • #6
doesn't g/M mean g/mol/L?
 
  • #7
its not exactly 12, and its not exactly 16 for oxygen either

but they decided to make it 12 anywho. so just use 12 as a whole number

6 protons = 6 x 1.007277 6.043662
6 neutrons = 6 x 1.008665 6.051990
6 electrons = 6 x 0.000548 0.003288
Total 12.098940
 
Last edited:
  • #8
Carbon was easy to purify, that is why they used it as a reference and why it is the whole number 12.
 

Related to Molecular Weight for nucleotides

1. What is molecular weight for nucleotides?

The molecular weight for nucleotides is the sum of the atomic weights of all the atoms in a nucleotide. It is measured in atomic mass units (amu) or kilodaltons (kDa).

2. Why is molecular weight important for nucleotides?

The molecular weight of a nucleotide is important because it affects its physical and chemical properties. It can also impact its function and interactions with other molecules in biological processes.

3. How is molecular weight for nucleotides calculated?

Molecular weight for nucleotides is calculated by adding the atomic weights of each atom in the nucleotide. For example, the molecular weight of adenine (A) is calculated by adding the atomic weights of carbon (C), nitrogen (N), hydrogen (H), and oxygen (O) present in adenine.

4. What is the average molecular weight for nucleotides in DNA?

The average molecular weight for nucleotides in DNA is approximately 324.5 g/mol. This value can vary depending on the specific sequence and composition of the DNA molecule.

5. Why do different nucleotides have different molecular weights?

Different nucleotides have different molecular weights because they contain different combinations of atoms. For example, adenine has a different molecular weight than guanine because they have different numbers of carbon, nitrogen, hydrogen, and oxygen atoms.

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