Dismiss Notice
Join Physics Forums Today!
The friendliest, high quality science and math community on the planet! Everyone who loves science is here!

Mutagen - Ethidium Bromide

  1. Aug 3, 2006 #1
    This Monday I have to goto Melbourne to do 2 SACs in one day (For non-Australians they are basically assesed assignments) having to do just with general genetics.

    Anyway they say that we should use gloves etc. blah blah blah safety stuff, because we'll be handling Ethidium bromide (in the form of eletrophoresis gels is my guess) which is a mutagen.

    My question is why type of mutations/symptoms can be expected if you're exposed to Ethidium bromide? (Just curious =p)

    ~Gelsamel
     
  2. jcsd
  3. Aug 3, 2006 #2

    iansmith

    User Avatar
    Staff Emeritus
    Science Advisor
    Gold Member

    Ethidium bromide is an intercalating agent, so it bind to DNA and will force replication errors, so it impossible to predict the symptoms that will results from this mutation but cancer can be one.

    Ethidium bromide is also an irritant of the skin, the eye and respiratory tract. Also, latex gloves do not protect as well as nitril, ethidum bromide can go trough latex gloves if it's in large concentration/quantity. Trust me I learn this one the hard way.
     
  4. Aug 3, 2006 #3

    NoTime

    User Avatar
    Science Advisor
    Homework Helper

    Latex is useless. :grumpy:

    Just about any chemical will go through it, if it doesn't outright disolve it first.
    Might be ok to keep big clunky bacteria off your skin, but that's about it.
     
Know someone interested in this topic? Share this thread via Reddit, Google+, Twitter, or Facebook

Have something to add?



Similar Discussions: Mutagen - Ethidium Bromide
Loading...