Myostatin, mice and meat

  • Thread starter Golgot
  • Start date
  • #1
Golgot

Main Question or Discussion Point

Hi all,

Does anyone know where I can get some concrete information on the original experiments with mice which had their myostatin gene knocked out (I believe, altho myostatin "blocking" seems to be the technique that is now prefered) ...and here's the important bit....they gained 2-3 times the normal muscle mass, but also became notably unaggressive/timid. I have several sources containing circumstantial evidence, but none of the original investigators seem to have documented these findings.

Can anyone help?

Also, does anyone know whether myostatin products have really found their way into the meat industries and body building communities (plus do you know of any known or potential side-effects involved).

Thanks for any help

Tom
 

Answers and Replies

  • #2
Ygggdrasil
Science Advisor
Insights Author
Gold Member
2019 Award
3,031
2,642
This reference appears to the be the original paper describing the myostatin knockout mouse (myostatin was previously named GDF-8): https://www.ncbi.nlm.nih.gov/pubmed/9139826

The paper does not mention any behavioral phenotypes, though that would not be evidence that such phenotypes do not exist.
 

Related Threads on Myostatin, mice and meat

  • Last Post
Replies
1
Views
829
  • Last Post
Replies
3
Views
2K
Replies
1
Views
773
  • Last Post
Replies
1
Views
36K
  • Last Post
Replies
5
Views
2K
Replies
1
Views
2K
  • Last Post
Replies
1
Views
2K
  • Last Post
Replies
14
Views
4K
  • Last Post
Replies
1
Views
2K
  • Last Post
Replies
1
Views
2K
Top