Neuroscience -- Action Potentials, Voltage Clamps I'm trying to do a Neuroscience assignment and I'm a little confused about action potential behaviors especially when dealing with voltage clamps. First, when you are trying to measure the rate of an action potential propagation would you measure the voltage changes or the current change across the membrane? I thought that it should be the voltage change since AP's depolarize and polarize the membrane. Also, when you use a voltage clamp on an axon can an action potential still propagate? I'm thinking that it can't since a voltage clamp is a way to artificially measure potentials. I'm really not positive about either question so any advice would be great! Thanks!