The problem is that they use an adenovirus, which is immunogenic: patients' immune respons can react very fiercely when a wrong dose is given for instance. The other problem with this virus is that the expression of the gene is only transient.The treatment consists of an adenovirus designed to insert a gene called p53. This gene codes for a protein that triggers cell suicide when cells start to run amok, preventing them becoming cancerous.
Many tumours arise after the mutation or inactivation of p53, and in cancers of this type restoring the protein should kill the tumour cells. This approach has already been tried in the US, with mixed results.
You're right, plenty of efficient biological warfare means to kill people. I just envisioned training a dendritic cell to attack something which is found everywhere, or maybe just in your brain or liver or something. Then, making a virus which will cause your dendritic cells to act that way.Originally posted by Monique
How do you envision it being applied as a biological weapon? I really don't think that is feasible in this manner :) there are much easier ways to attack every cell in someones body by using conventional methods like microorganisms or toxins, nothing new under the sun.