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Serenie
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The topic in the prize is about GPCR and from what i have researched, the research is about biology. I want to know why it was rewarded to the field in chemistry.
Probably because they were working at the chemistry level with methods methods that were as much chemistry as physilogy or medicine.The topic in the prize is about GPCR and from what i have researched, the research is about biology. I want to know why it was rewarded to the field in chemistry.
Lefkowitz started to use radioactivity in 1968 in order to trace cells' receptors. He attached an iodine isotope to various hormones, and thanks to the radiation, he managed to unveil several receptors, among those a receptor for adrenalin: β-adrenergic receptor. His team of researchers extracted the receptor from its hiding place in the cell wall and gained an initial understanding of how it works.
The Nobel Prize in Physiology or Medicine 2012 was awarded jointly to Sir John B. Gurdon and Shinya Yamanaka "for the discovery that mature cells can be reprogrammed to become pluripotent"