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Nucleoli and nucleus

  1. Mar 23, 2016 #1
    If nucleoli does not have a clear membrane,wouldn't it get mixed up with substances in the nuclear matrix present in the nucleus ?
  2. jcsd
  3. Mar 24, 2016 #2


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    The nucleolus is though to separate itself from the rest of the nucleoplasm via physical mechanisms resembling phase separation (like how oil droplets can separate from water). This is a very active area of research with many new results in the past couple of years. Here's a recent review on the topic: http://www.sciencedirect.com/science/article/pii/S0955067415000435
    Last edited: Mar 24, 2016
  4. Mar 24, 2016 #3
    That's the perfect answer.Thank you :smile:
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