Can Nutrie Skinne Help with Weight Loss for Those with Thyroid Issues?

[Greg Bernhardt]

I have a friend who told me they are interested in this new weight loss product. I am always highly skeptical of such products, but the friend said she knows someone who lost 6lbs in two weeks without changing anything else. Anything in here that looks promising or is this more fools gold?Skinné's ingredients:

CLA Oil Omega 6 B Vitamin, energy increase
Garcinia Cambogia; Suppress appetite and enhance fat-burning Chromium picolinate, Decreases sugar cravings, regulates blood sugar control Rhodiola 300 MG, Decreases cortisol, increases energy without a buzz Magnesium Calmative

Nutrition label:

 

[Evo]

Garcinia - Weight loss. Taking garcinia fruit rind extract doesn't seem to decrease weight, fat breakdown, or energy expenditure in overweight people. There is some mixed evidence that garcinia might help people feel full even when eating less, but it's too early to recommend garcinia for this use.

http://www.webmd.com/vitamins-suppl...ngredientId=818&activeIngredientName=GARCINIA

CLA - Obesity. Conjugated linoleic acid might help decrease body fat, but it does not seem to decrease body weight.

Omega 6 - Supplements should not be taken except under a doctor's care for specific resaons.

http://en.wikipedia.org/wiki/Omega-6_fatty_acid#Negative_health_effects

The average diet provides sufficient omega-6 fatty acids, so supplementation is usually not necessary unless you're treating a specific condition, such as eczema or psoriasis, arthritis, diabetes, or breast tenderness (mastalgia).

Because of the potential for side effects and interactions with medications, dietary supplements should be taken only under the supervision of a knowledgeable health care provider.

http://www.umm.edu/altmed/articles/omega-6-000317.htm

chromium picolinate

Insufficient evidence for: Obesity and weight loss. Taking chromium picolinate by mouth for 2 to 3 months might produce a small weight loss of about 1.1 kg. But not all studies have found this benefit.

Possibly ineffective for:

Athletic performance. Reliable studies show that taking chromium by mouth doesn’t seem to enhance body building, strength, or lean body mass.
Prediabetes.

http://www.webmd.com/vitamins-suppl...ngredientId=932&activeIngredientName=CHROMIUM

It's the same for everything they list. Are they eating less carbs? The weight loss could just be temporary water loss.

 

[Ben Niehoff]

The weight loss could just be temporary water loss.

I was under the impression that this is how most of these "miracle weight loss" items work. So you might lose an impressive amount of weight in the first week or two, but it won't continue. I do notice that it contains 100mg of caffeine; I don't know if that's "a lot" or not, but it certainly aids water loss. I don't know if any other ingredients might also be diuretics.

Caffeine has the added effect that it can make you feel energetic without having any calories. It's a popular supplement among body builders during their "cutting" phase. Gives you some extra oomph to push it in the gym without eating extra food.

Of course, these "miracle weight loss" things are often marketed with the implication that there's no need to do actual exercise alongside them.

 

[Evo]

I was under the impression that this is how most of these "miracle weight loss" items work. So you might lose an impressive amount of weight in the first week or two, but it won't continue. I do notice that it contains 100mg of caffeine; I don't know if that's "a lot" or not, but it certainly aids water loss. I don't know if any other ingredients might also be diuretics.

Caffeine has the added effect that it can make you feel energetic without having any calories. It's a popular supplement among body builders during their "cutting" phase. Gives you some extra oomph to push it in the gym without eating extra food.

Of course, these "miracle weight loss" things are often marketed with the implication that there's no need to do actual exercise alongside them.

Yes, I was wondering how much effect the caffeine would have on water loss. I see it added to many weight loss products.

 

[jim mcnamara]

Guarana (455mg) is a caffeine analog used in a lot of drinks, particularly in Latin America. One pill also has 100mg of caffeine.

So that is 555mg of caffiene-like "stuff".

So let's see here: a cup of coffee made with a teaspoon of instant coffee: 31 mg of caffeine
http://ndb.nal.usda.gov/ndb/foods/s...t=&count=&max=25&offset=&sort=&qlookup=coffee

Coffee brewed from grounds 1 cup: 95mg of caffeine
http://ndb.nal.usda.gov/ndb/foods/s...t=&count=&max=25&offset=&sort=&qlookup=coffee

The total load of caffeine analogs in one pill exceeds five cups of coffee. Sounds like the person you mentioned should be really careful first and get medical help. This stuff is worse than "no-doz" pills @100mg caffeine per pill. Did the person turn into 'buzzy the hummingbird'? ( if you ever read Calvin and Hobbes)
http://www.nodoz.com.au/faq.php

 

[Viracocha]

If you really want weight loss try using caffeine or other energy boosters mainly to fuel an exercise routine, but they won't burn too much on their own

 

[Aero51]

Garbage, don't even consider this bull.

Weight loss is (barring any medical conditions) achieved through a healthy diet and exercise. Always dismiss any kind of diet miracle mumbo-jumbo.

she knows someone who lost 6lbs in two weeks without changing anything else

3lbs a week... that's 3500*3 = 10500 calories a week, divide by 7 is a diet of no greater than 1500kcal a day, not including and personal considerations such as BMR, activity level, etc. For a woman, maybe that is achievable. For a man this is the boarder line between a normal metabolism and one that is in "survival mode", depending on your basal metabolic rate. Where do the calories go? Are they sucked into a black hole? Perhaps is it sorcery? Is this pill some type of genius engineering of porous media that only absorbs fat?

From a practical standpoint, I ran the caloric intake estimates for a 30 year old, 200lb, sedentary man.
<http://www.calculator.net/calorie-calculator.html?ctype=standard&cage=30&csex=m&cheightfeet=6&cheightinch=0&cpound=200&cheightmeter=180&ckg=60&cactivity=1.2&x=71&y=8>
These are the results:

you need 2286 Calories/day to maintain your weight
you need 1786 Calories/day to lose 1 lb per week
you need 1286 Calories/day to lose 2 lb per week
you need 2786 Calories/day to gain 1 lb per week
you need 3286 Calories/day to gain 2 lb per week

To lose 3 pounds per week a man of these dimensions would require 786 kcal a day! Do you know how much food that is?
<http://caloriecount.about.com/calories-mcdonalds-double-quarter-pounder-cheese-i53969>

1 double quarter pounder and an apple.

Now, if this is your only meal and you eat it sometime in the afternoon, You can bet after a a few hours your metabolism will go into starvation mode and begin breaking down your muscle and fat.


Not to be a jerk, but tell your friend to quit being lazy, get a gym membership, and eat healthy.

 

[Aero51]

Even more staggering is this calculation I ran: a 160 lb woman, 30 years old, no exercise, 5'5" yields the following:

you need 1736 Calories/day to maintain your weight
you need 1236 Calories/day to lose 1 lb per week
you need 736 Calories/day to lose 2 lb per week
you need 2236 Calories/day to gain 1 lb per week
you need 2736 Calories/day to gain 2 lb per week

To lose 3 lb/week requires only 236 calories a day! Obviously, the approximations made with this calculator may not be valid for the aforementioned goal.

Regardless, 236 calories a day is about... 2 chicken breasts, meat only.
http://caloriecount.about.com/calories-chicken-breast-meat-only-i5064


Good luck with that!

 

[Greg Bernhardt]

Thanks for the information everyone! I'm going to look deeper into this. If anyone else has any experience or further thoughts on the ingredients I'd love to hear it!

 

[Greg Bernhardt]

Here is a journal paper that seems to support Garcinia for appetite suppression.
http://www.hindawi.com/journals/ecam/2012/197920/abs/

 

[Evo]

Here is a journal paper that seems to support Garcinia for appetite suppression.
http://www.hindawi.com/journals/ecam/2012/197920/abs/

That link takes to me to paper discussing toxicity.

 

[Greg Bernhardt]

After some research I found this information of the Nutrie Skinné ingredients from pretty good (not great) sourceschromium picolinate

http://www.vanderbilt.edu/AnS/psychology/health_psychology/chromiumpicolinate.htm

"Despite rampant claims that chromium picolinate is a weight loss miracle that will melt fat, improve metabolism, and increase muscle mass, scientific evidence overwhelmingly indicates that the supplement does nothing of the kind. When combined with exercise, chromium supplementation does nothing to enhance weight loss as compared to exercise alone, in study after study. The case of chromium picolinate should caution consumers against believing miracle weight loss claims."

"These diet compounds, which are readily available over the internet, often combine chromium picolinate with L-carnitine, with guarana and ma huang, or with dangerous diuretics. Such combination tablets are risky, as any interactions between chromium picolinate and other supplements remain unknown at this time"http://health.howstuffworks.com/wellness/natural-medicine/alternative/chromium-picolinate3.htm

"More and more studies are showing that chromium picolinate's negative effects are quite drastic. Two reputable studies have shown that it can trigger mutations in DNA as a result of reactions with other elements found in the body [source: Women Fitness]. These elemental reactions have an adverse effect on DNA, which may cause cancer [source: UC Berkeley Wellness Letter]. Other, less severe reactions may result from the dangerous compounds created from these elements. In addition, since picolinate isn't found naturally occurring with chromium, the picolinate may eventually break apart from the chromium and have negative effects [source: Women Fitness]."

"Fitting with the FTC's complaint against the three California companies marketing chromium picolinate, scientific research has not been able to support the claims that chromium picolinate helps people lose weight. Several studies conducted during the late 1990s, when chromium picolinate really started to soar in popularity, indicate that chromium picolinate does not contribute to more lean muscle or decreased fat in the body [source: Allen]."Garcinia

http://www.webmd.com/vitamins-suppl...ngredientId=818&activeIngredientName=GARCINIA

"Developing research suggests that garcinia might prevent fat storage and control appetite; however, whether these effects occur in humans is unclear."

"Taking garcinia fruit rind extract doesn't seem to decrease weight, fat breakdown, or energy expenditure in overweight people. There is some mixed evidence that garcinia might help people feel full even when eating less, but it's too early to recommend garcinia for this use."

"Garcinia is POSSIBLY SAFE for most people when used for 12 weeks or less. Long-term safety is unknown. Garcinia can cause nausea, digestive tract discomfort, and headache."http://www.ncbi.nlm.nih.gov/pubmed/22530711

"Although several studies have found that the administration of G. cambogia extracts is associated with body weight and fat loss in both experimental animals and humans, we should be cautious when interpreting the results as other randomized, placebo-controlled clinical trials have not reported the same outcomes. Furthermore, most studies in humans have been conducted on small samples and mainly in the short term. None of them have shown whether these effects persist beyond 12 weeks of intervention. Therefore, there is still little evidence to support the potential effectiveness and long-term benefits of G. cambogia extracts"http://www.med.nyu.edu/content?ChunkIID=21727/

"Although animal and test tube studies as well as two human trials suggest that HCA might encourage weight loss , other studies have found no benefit"

"A 12-week double-blind trial of 89 individuals found that HCA had no effect on appetite. 18 Another study tested HCA to see if it could cause weight loss by altering metabolism, but no effects on metabolism were found."Rhodiola

http://www.med.nyu.edu/content?ChunkIID=111798

"One small double-blind trial performed in Belgium did find evidence that use of a different rhodiola extract at a dose of 200 mg 1 hour before endurance exercise may improve performance. 5 However, another study failed to find benefit with a combination of cordyceps and rhodiola."

http://en.wikipedia.org/wiki/Rhodiola_rosea

"Two systematic reviews on R. rosea extracts concluded that the research evidence is contradictory, and definite conclusions over its efficacy to relieve mental and physical fatigue are hampered by the lack of rigorously-designed, well-controlled randomized control trials"Conjugated linoleic acid

http://www.webmd.com/vitamins-suppl...activeIngredientName=CONJUGATED LINOLEIC ACID"Conjugated linoleic acid might help decrease body fat, but it does not seem to decrease body weight."

http://www.bodybuilding.com/fun/mike8.htm

"Swedish researchers reported in December, 2000 that CLA takes away fat while increasing muscle mass. The study found that approximately 3.4 grams of CLA per day is the level needed to obtain the beneficial effects of CLA on body fat" (skinny only has 500mg)

http://en.wikipedia.org/wiki/Conjugated_linoleic_acid

"Some studies have found no significant effects of CLA supplementation on fat mass loss"Raspberry Ketones

http://www.huffingtonpost.com/becky-hand/raspberry-ketones_b_2727943.html

"Raspberry ketones have never been tested on humans in scientific studies."

http://www.webmd.com/vitamins-suppl...Id=1262&activeIngredientName=RASPBERRY KETONE

"Raspberry ketone became popular for weight loss after it was mentioned on the Dr. Oz television show during the segment called “Raspberry ketone: Miracle fat-burner in a bottle” in February 2012. Even though it is touted as a “miracle” for weight loss, there is no reliable scientific evidence that it works for improving weight loss."Guarana

http://www.webmd.com/vitamins-and-supplements/lifestyle-guide-11/supplement-guide-guarana

"Researchers once believed that the active ingredient of guarana was a chemical specific to the plant -- guaranine. But they later discovered that it was just caffeine. Guarana has among the highest concentrations of caffeine in any plant. It may contain up to 3.6% to 5.8% caffeine by weight. Coffee only has up to 2%."

"High doses of caffeine may raise the risk of increased heart rate, breast disease, and high blood pressure. An overdose of caffeine can cause seizures and convulsions. Talk to your doctor before using guarana if you have high blood pressure, anxiety disorders, glaucoma, osteoporosis, heart problems, bleeding disorders, diabetes, kidney problems, or liver disease. At least one death has been reported in a young woman with mitral valve prolapse who consumed a guarana containing drink. People with MVP should speak to their doctor before using guarana."

"There’s some evidence that guarana – when used along with other supplements – may promote weight loss. It’s uncertain if the guarana specifically was responsible."

 

[Greg Bernhardt]

Just heard back from a spokesman for the company and they said the product is FDA approved and that the "455mg of guarana in Skinne, produces the 100mg of caffeine".

 

[Aero51]

Out of curiosity, why are you so interested in this product? Exercise and diet will beat this garbage hands down. I personally lost 30lbs by cutting calories and avoiding sweets.

 

[Evo]

Everything Greg has posted says the product doesn't work.

 

[Greg Bernhardt]

Everything Greg has posted says the product doesn't work.

The research I posted says either an ingredient doesn't work, is inconclusive or there could be a marginal benefit.

Out of curiosity, why are you so interested in this product? Exercise and diet will beat this garbage hands down. I personally lost 30lbs by cutting calories and avoiding sweets.

My friend uses it and claims to feel better, lost several pounds and not have the urge to eat as much. I think the last part is more important. That could be the Garcinia. Tribes have used Garcinia for hundreds of years to suppress appetite. If that is the case, it might be better just to buy Garcinia pills and skip the rest.

 

[Evo]

It could also be placebo effect, if they believe they are not going to feel hungry...

Its safety is in question.

Extracts of the exocarp of certain species – typically G. gummi-gutta, but also purple mangosteen – are often contained in appetite suppressants such as Hydroxycut, Leptoprin or XanGo. But their effectiveness at normal consumption levels is unproven, while at least one case of severe acidosis caused by long-term consumption of such products has been documented.[3] Furthermore, they may contain significant amounts of hydroxycitric acid, which is somewhat toxic and might even destroy the testicles after prolonged use.[4]

http://en.wikipedia.org/wiki/Garcinia#Uses

 

[Greg Bernhardt]

It could also be placebo effect, if they believe they are not going to feel hungry...

No doubt, we'll have to wait and see what the results are after a few months.

Its safety is in question.

http://en.wikipedia.org/wiki/Garcinia#Uses

To play devils advocate, "at least one" isn't very high. They claim the FDA has approved the drink. Even Aspirin can have some nasty side effects.

 

[Evo]

They claim the FDA has approved the drink. Even Aspirin can have some nasty side effects.

If they claim that...RUN!

Is It Really FDA Approved?

Dietary Supplements and FDA

Dietary supplements, in general, are not FDA-approved. Under the law (Dietary Supplement Health and Education Act of 1994), dietary supplement firms do not need FDA approval prior to marketing their products. It is the company’s responsibility to make sure its products are safe and that any claims are true.

Just because you see a supplement product on a store shelf does NOT mean it is safe or effective. When safety issues are suspected, FDA must investigate and, when warranted, take steps to have the product removed from the market. However, it is much easier for a firm to get a product on the market than it is for FDA to take a product off the market.

FDA has worked with industry to recall more than 40 products marketed for weight loss with potentially harmful ingredients, and has issued consumer alerts about dozens more. The agency also has issued warning letters, seized products, and criminally prosecuted people responsible for these illegal diet products.

FDA cannot test all products on the market to identify those that contain potentially harmful hidden ingredients. FDA has created an RSS feed to alert consumers more rapidly when FDA finds a tainted product.

This article appears on FDA's Consumer Updates page, which features the latest on all FDA-regulated products.

http://www.fda.gov/ForConsumers/ConsumerUpdates/ucm047470.htm

http://www.fda.gov/ForConsumers/ConsumerUpdates/ucm246742.htm

Their website says

information on this website has not been reviewed by the Food and Drug Administration

I agree with you that many everyday products that we consider safe can easily become dangerous if used incorrectly, or if you have a condition that is aggravated by the product.

Permanent weight loss can only be achieved, IMO, by a lifestyle change. Some drugs are known to reduce or increase weight, it's a fact, but they are prescription. So I'm sure some natural foods could possibly have a very mild effect, but if they worked well and consistently, it would be splashed across the news.

BTW, due to elevated levels of iron, I have elevated levels of blood sugar, so I am on metformin (glucophage), and it does cause a very quick 10% loss of body weight. Some people take it just for the weight loss.

 

[THyroid]

Exercises and diet actually work for people that don't suffer from Hashimoto's Thyroid or Hypothyroidism. Sometimes, people judge fat or overweight people as lazy or presume that they can't stay away from sweets and the table.

I was skinny my entire life, I am also vegetarian since teenager years and don't drink soda, I avoid gluten, but since I turned 40yo my body just changed. I practice Yoga and Pilates, Hidrofitness and not matter what I tried I was gaining weight every month.

Labs results came out normal, but finally, I discovered that I have a thyroid dysfunctional that I am still struggling to fix. I will try any product that gives me extra energy and helps me to fight fat.

We should be more compassionate about fat and don't be so quickly to judge.