How do operons interfere with DNA replication, if at all? I know, for example, that repressors can stop RNA polymerase, keeping a segment from being transcribed, but it's still replicated. How is this? My guesses are: A. The enzymes involved in DNA replication can run right over them. or B. All operons are temporarily activated during DNA replication. Or, of course, something completely different... Any help is appreciated! Thanks.