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What is the intracellular sorting mechanism called where a protein is transported by another protein?
Piggy back/ Piggyback
or
Piggy bag/ Piggybag?
Piggy back/ Piggyback
or
Piggy bag/ Piggybag?
You are right, but that is something else. Chaperone is not a mechanism for directing a protein to the lysosome or ER etc.Originally posted by iansmith
Protein that guide other protein are called chaperon. It probably called chaperoning
You are right, but that is something else. Chaperone is not a mechanism for directing a protein to the lysosome or ER etc.
A group of proteins that guide other proteins during their synthesis and assembly at the ribosome and their subsequent transport to their site of action
Cytoplasmic proteins of both prokaryotes and eukaryotes that bind to nascent or unfolded polypeptides and ensure correct folding or transport. Chaperone proteins do not covalently bind to their targets and do not form part of the finished product. Heat-shock proteins are an important sub set of chaperones. Three major families are recognised, the chaperonins (groEL and hsp60), the hsp70 family and the hsp90 family. Outside these major families are other proteins with similar functions including nucleoplasmin, secB and T-cell receptor associated protein.
Oh, really. So chaperoning is the word to be used.. then I learned something new today since the word piggyback has been the only term that I heard :) no wonder I didn't find much on google. Thanks Ian.Originally posted by iansmith
Piggybacking appears to be more than a laymen word rather than the actual word use. Very article use piggybacking as the mecahnism for chaperoning.
From what I just read, piggybacking could be the transport of protein that are not newly synthesis and are staying in the cytoplasm. For example, protein that are activated after the signal transduction cascade and act in the on the DNA.
Originally posted by Monique
Oh, really. So chaperoning is the word to be used.. then I learned something new today since the word piggyback has been the only term that I heard :) no wonder I didn't find much on google. Thanks Ian.
Originally posted by Monique
What is the intracellular sorting mechanism called where a protein is transported by another protein?
Piggy back/ Piggyback
or
Piggy bag/ Piggybag?
Chaperoning could also imply folding and error fixing (not transporting directy). As I know chaperons basically help proteins in transporting through the membranes by defolding them on the entrance and properly folding them on exit, and keeping their proper 3D structure during the transport in the cell. Beside that family of chaperones include HSP molecules (mainly), and you know their purpose.Originally posted by Monique
But apparently chaperoning is the correct term.
A piggy back/bag is a type of transportation method where one object is carried on the back of another object. It can also refer to a bag or container that is attached to the back of a person or animal for carrying items.
In terms of transportation, piggy back/bag works by using the strength and stability of one object to support and carry another object. This is often seen in the transportation of goods on trucks or trains, where containers are stacked on top of each other. In terms of carrying items, a piggy back/bag attaches to the back of a person or animal and allows them to easily carry items without using their hands.
The use of piggy back/bag can save time and effort in transporting goods, as it allows for multiple items to be carried at once. It can also reduce the risk of injury for the carrier, as they do not have to physically carry the items with their hands. Additionally, piggy back/bag can be more efficient and cost-effective for transportation companies.
One potential downside to using piggy back/bag is the risk of imbalance or instability, which can lead to accidents or damage to the items being transported. There may also be limitations on the size and weight of items that can be carried using this method. Additionally, in terms of carrying items, the piggy back/bag may cause strain or discomfort for the carrier if it is not properly balanced or adjusted.
In scientific research, piggy back/bag can be used as a method of sample collection or transportation. For example, a researcher may use a piggy back/bag to carry equipment or specimens while conducting fieldwork. It can also be used in laboratory settings to transport samples or materials between different workstations or experiments.