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sotellme
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What is polyclonal antiserum? I have checked the net, but could not find any good explanation on it. :grumpy:
Thanks.
Thanks.
Polyclonal antiserum is a type of serum that contains a mixture of antibodies produced by different B cells in response to a specific antigen.
Polyclonal antiserum is produced by injecting an animal, usually a rabbit or goat, with a specific antigen. The animal's immune system will respond by producing a variety of antibodies against the antigen. The antibodies are then collected from the animal's blood and purified to create the polyclonal antiserum.
Polyclonal antiserum contains a mixture of antibodies produced by different B cells, while monoclonal antiserum contains only one type of antibody produced by a single clone of B cells. Monoclonal antiserum is produced in a laboratory through cell culture techniques, while polyclonal antiserum is produced in animals.
Polyclonal antiserum is commonly used in research and diagnostic applications to detect and quantify specific antigens. It can also be used therapeutically to treat certain diseases and conditions by providing passive immunity.
One potential concern with using polyclonal antiserum is the presence of non-specific antibodies, which may bind to unrelated antigens and produce false positive results. Additionally, the production of polyclonal antiserum in animals can raise ethical concerns and there may be batch-to-batch variability in the composition of the antiserum.