I have a huge set of data. About 5000 excel sheets and in each one about a 500x7 matrix. I'll be doing a lot of manipulation where I'll need a programming environment that is faster than excel (excel is pretty slow). Anyone have experience with both R and Matlab and can comment on which one is faster? Just to give an idea of what I will be doing, out of those 5000 matrices, I will have to do some work with every combination of 2 from the total 5000. So I will have 5000 C 2 combinations or 12,497,500 combinations. After I choose which two matrices I'll work with, I will have to do things like addition, multiplication, and regression analysis on specific columns in the two matrices.