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Homework Help: Reductions of C=O

  1. Oct 17, 2005 #1
    Can someone please tell me the difference between Clemensen's reduction and the Wolf-Kisher reduction?
  2. jcsd
  3. Oct 17, 2005 #2
    Well, they're related in that they both reduce ketones to the methylene.

    The obvious difference is that one's acidic while the other's basic.

    Clemmensen uses zinc and a strong acid, while Wolff-Kishner uses hydrazine and a base, often hydroxide.
  4. Oct 17, 2005 #3


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