Seems like a pretty basic thermodynamics question, but i can't think of a way how or get a clear reason why not. Let's take a heat-insulated room with a usable energy source provided in it (electric wires sticking out of a wall). Can this room be refrigerated as a whole? One thing is, any refrigeration scheme i've seen requires a heat sink besides a power source, so one half of the room would have to be made hotter to get the other half colder, and since whatever way is used would add more heat to what it moves, the overall temperature would increase until the power runs out. First law of thermodynamics. On the other hand, why can all the excess of heat/entropy be generated on the other side, where the energy source is? Energy can be use to order things, and ordering things reduce entropy. There are ways to slow atoms down directly on small scale. So, is it a fundamental or technical problem?