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Medical Rhesus Negative Conundrum

  1. Sep 3, 2014 #1
    So there I was thinking, if the mother was Rhesus Negative and she had a Rhesus positive baby, her antibodies would cross the placenta and attack the Rhesus positive baby's red blood cells (assuming second child).

    Then I thought, well, what if the mother was Rhesus positive, and the baby was Rhesus negative?

    Well...firstly, Rhesus positive (Rh+) is dominant, yes? It causes the expression of the important "D" antigen on the surface of RBC. Therefore, a Rhesus positive mother and a Rhesus negative father would give a Rhesus positive baby. Therefore, we can conclude that the mother can never be Rhesus positive while the foetus/(baby) was Rhesus negative or at least...this scenario is unlikely?!

    But wait...

    What if, we took a Rh- mother's egg, and a Rh- father's sperm, fertilised it and through IVF placed it in a Rh+ SURROGATE mother? What effects would occur?!

    Would nothing occur because the foetus does not produce antibodies at all?

    - Cobby

    P.S. Yes I just wanted to let you know I went through the thought process...took a while to get to the question :)
  2. jcsd
  3. Sep 12, 2014 #2
    I'm sorry you are not finding help at the moment. Is there any additional information you can share with us?
  4. Sep 13, 2014 #3
    Nope..no additional information...that's ok thanks for asking! I'm going to ask some university lecturers too so if I get the answer I'll let ye all know :)
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