Is TMEM108 Effective for Treating Schizophrenia in Humans?

In summary, the article discusses how mutations in a gene linked to schizophrenia can lead to communication issues between neurons. The research on mice shows that reducing the protein expression of this gene results in fewer and smaller spines, which are important for neuron communication. This research has potential implications for humans and could lead to similar treatment options for individuals with schizophrenia.
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wolram
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I have found this article about schizophrenia, It talk's about TMEM working on mice, I wonder if there is similar
treatment for humans.
https://www.sciencedaily.com/releases/2017/01/170118163751.htmMutations in a gene that should enable memories and a sense of direction instead can result in imprecise communication between neurons that contributes to symptoms of schizophrenia, scientists report.

They found that dramatically reducing the amount of protein expressed by TMEM108, a gene already associated with schizophrenia, results in fewer, smaller spines, which work like communication fingers for neurons, said neuroscientist Dr. Lin Mei.
 
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What is schizophrenia?

Schizophrenia is a mental disorder characterized by abnormal social behavior and failure to understand reality. It often involves delusions, hallucinations, and disorganized thinking and speech.

Can mice exhibit symptoms of schizophrenia like humans?

Yes, mice can exhibit behaviors that mimic symptoms of schizophrenia in humans, such as decreased social interaction, impaired cognitive function, and altered neurotransmitter levels.

How do scientists study schizophrenia in mice?

Scientists use various behavioral and biochemical tests to study schizophrenia in mice. This can include maze tests, social interaction tests, and measuring levels of neurotransmitters in the brain.

What can studying schizophrenia in mice tell us about the disorder in humans?

Studying schizophrenia in mice can provide valuable insights into the underlying causes and mechanisms of the disorder in humans. It can also help researchers develop and test potential treatments.

Can findings from studies on schizophrenia in mice be directly applied to humans?

No, findings from studies on schizophrenia in mice cannot be directly applied to humans. While mice can exhibit similar behaviors and biological changes, they are still different from humans and therefore, findings must be carefully interpreted and further studied in human subjects.

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