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Sperm, egg and aging

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  1. Apr 24, 2016 #1
    So, if the male is age 30 and the female is age 28 with the sperm and egg, why isn't their baby starts at age 29? That means the DNA damage theory shouldn't happen, each male and female would give half of their chromosomes (23) created through meiosis and fuse them to form a zygote beginning at age zero. If DNA damage theory does happen, somewhere along the line there would have been a perfect repair of DNA. So what do you think is the difference in age between the zygote and the male and female?
     
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  3. Apr 24, 2016 #2

    Choppy

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    From a genetic point of view, who says that it doesn't? From a certain point of view you could consider specific genes (or perhaps the genes' codes) to be millions or even billions of years old.

    I think one important thing to remember is that the phenomenon of age as we experience it, is more than just an accumulation of genetic damage. And I don't think there's any requirement for the DNA to be "perfect" - whatever that means. It needs to be functional, but that's about it.
     
  4. Apr 24, 2016 #3

    Evo

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    It would really help if you would post links to what you've read that has lead to your misunderstandings so that we can clarify for you.

    This is an article about how the age of the mother can impact the viability of the egg. There is a lot of information how children of older mothers are more prone to birth defects. you just need to do some simple searches.

    http://science.psu.edu/news-and-events/2014-news/Makova10-2014
     
    Last edited: Apr 24, 2016
  5. Apr 24, 2016 #4

    jim mcnamara

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    Whew. I'm not posting citations - there are too many required. Simply and without lots of technical terms:
    1. Human females begin meiosis as a fetus. It is "held" midway until ovulation. A woman 28 years old has "eggs" that have been on hold for 28 years, (take away about 4 months).
    2. Human males continuously undergo meiosis. So complete "sperm creation" takes less than 45 days or so.

    Meiotic failures increase as a function of the woman's age versus when the "egg" started meiosis. Therefore defects which relate to 'goofed-up' meiosis, like Down's Syndrome, increase as a percentage of live births as Mom gets older. Not necessarily as Dad gets older. Dad can have problems, too. They are just not as blatantly obvious. And not always directly age-related, like the meiotic problems Mom has.
     
  6. Apr 24, 2016 #5

    Evo

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    I think Jim has a good point, we would have to teach a course on reproduction to answer the OP's wrong and too broad questions. Thread closed. Op needs to do some searches, which would be very easy.
     
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