Tertiary Structure of DNA

  • #1

Another God

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Can DNA be supercoiled while it is wrapped around Histones?

We are often shown in Biology classes electron Photographs of Supercoiled DNA. Would this DNA in the picture be completely free of Histones? Or could the DNA visualised in the picture be supercoiled DNA already in its condensed Nucleosome structure?
 
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  • #2
I was under the impression that in vivo DNA that was wrapped around histones is predominately negatively supercoiled. Could be wrong.
 

1. What is the tertiary structure of DNA?

The tertiary structure of DNA refers to the three-dimensional arrangement of the double helix. It is the highest level of organization of DNA and is responsible for its stability and function.

2. How is the tertiary structure of DNA formed?

The tertiary structure of DNA is formed by the folding and coiling of the double helix. This is due to the interactions between the nitrogenous bases, specifically hydrogen bonding, and the backbone of the DNA molecule.

3. What is the role of the tertiary structure of DNA?

The tertiary structure of DNA plays a crucial role in gene regulation and expression. It also allows for the efficient packing of DNA into the cell nucleus and protects the genetic information from damage.

4. How does the tertiary structure of DNA differ from the secondary structure?

The secondary structure of DNA refers to the double helix shape, while the tertiary structure includes the folding and coiling of the double helix. The tertiary structure is also more complex and involves interactions between different parts of the DNA molecule.

5. Can the tertiary structure of DNA change?

Yes, the tertiary structure of DNA can change due to external factors such as changes in temperature, pH, or the presence of certain enzymes. This can affect the function and stability of the DNA molecule.

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