Tertiary Structure of DNA

  • #1
Another God
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Can DNA be supercoiled while it is wrapped around Histones?

We are often shown in Biology classes electron Photographs of Supercoiled DNA. Would this DNA in the picture be completely free of Histones? Or could the DNA visualised in the picture be supercoiled DNA already in its condensed Nucleosome structure?
 

Answers and Replies

  • #2
I was under the impression that in vivo DNA that was wrapped around histones is predominately negatively supercoiled. Could be wrong.
 

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