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Other Sciences
Biology and Medical
Viruses in Vaccines that can mutate and spread
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[QUOTE="Laroxe, post: 6284371, member: 555853"] In vaccination campaigns there are quite a few advantages to using the live vaccine, it provides a far more effective immune response, particularly in the tissues of the gut and the fact that the virus is excreted for up to six weeks can mean it acts as a booster to other people who come into contact with the vaccinated person. The virus is weakened to the point it is incapable of causing disease but among the weakened virus there may be a few that have retained their virulence but these are not at a level that can establish a clinical infection. So for the virus to become a problem it has to be repeatedly transmitted from person to person in a population in a way that allows the virus population in increase the percentage of potentially virulent organisms, this can only occur in populations with low vaccination rates and often requires other factors that impact on the levels of resistance. Because the virus has to deal with so many challenges vaccine derived outbreaks tend to be very limited, the virus rarely if ever reaching the level of virulence seen in the wild virus. The individuals most at risk tend to be the very young or those who are immunocompromised. Outbreaks are managed by attempts to increase the vaccine coverage to interrupt transmission, though the presence of the disease may increase distrust of the vaccine. There is a debate as to whether all polio vaccination should use the kill virus or subunit vaccines used in most countries, the problem is that while these carry no risk they are also far less effective. [/QUOTE]
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Viruses in Vaccines that can mutate and spread
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