All the ordinary matter we can find accounts for only about 4 percent of the universe. We know this by calculating how much mass would be needed to hold galaxies together and cause them to move about the way they do when they gather in large clusters. Another way to weigh the unseen matter is to look at how gravity bends the light from distant objects. Every measure tells astronomers that most of the universe is invisible. It's tempting to say that the universe must be full of dark clouds of dust or dead stars and be done with it, but there are persuasive arguments that this is not the case. First, although there are ways to spot even the darkest forms of matter, almost every attempt to find missing clouds and stars has failed. Second, and more convincing, cosmologists can make very precise calculations of the nuclear reactions that occurred right after the Big Bang and compare the expected results with the actual composition of the universe. Those calculations show that the total amount of ordinary matter, composed of familiar protons and neutrons, is much less than the total mass of the universe. Whatever the rest is, it isn't like the stuff of which we're made. The quest to find the missing universe is one of the key efforts that has brought cosmologists and particle physicists together. The leading dark-matter candidates are neutrinos or two other kinds of particles: neutralinos and axions, predicted by some physics theories but never detected. All three of these particles are thought to be electrically neutral, thus unable to absorb or reflect light, yet stable enough to have survived from the earliest moments after the Big Bang.