What's enhancer fusion?

  1. Also how is it different (if at all) from promoter fusion?
     
  2. jcsd
  3. atyy

    atyy 10,632
    Science Advisor

    Fusion just means you make a single DNA sequence by joining 2 or more other sequences. If one of the sequences is an enhancer, then the resulting joined sequence is an enhancer fusion. If one of the sequences is a promoter, then the resulting joined sequence is a promoter-fusion. You can, of course, get promoter-enhancer fusions, eg. "The process was analysed in transgenic flies carrying beta 1 enhancer-hsp70 promoter-lacZ fusion constructs."

    There isn't a strict distinction between promoters and enhancers.
    http://www.ncbi.nlm.nih.gov/books/NBK21745/#A2566
     
    Last edited: Nov 13, 2012
  4. Thanks a bunch.
     
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