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Why g-proteins has a shape of a helix?

  1. Feb 26, 2005 #1
    does anyone know why g-proteins has a shape of a helix??
     
  2. jcsd
  3. Feb 26, 2005 #2

    iansmith

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  4. Feb 27, 2005 #3

    Monique

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    G-proteins are stuck in membranes, thus they have a structure that allows them to be most stable.
     
  5. Feb 27, 2005 #4

    Moonbear

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    It's just the most chemically stable conformation of the protein. In a way, the question is asked a bit backward. The important question isn't why a g-coupled protein would form a helix, but why a helical structure would be advantageous to the function of a g-coupled protein. The simplified answer to that question is that it allows the hydrophobic region of the protein to interact with the hydrophobic cell membrane.
     
  6. Feb 27, 2005 #5

    Monique

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    Yes, the hydrophilic amino-acids can turn inwards of the helix in a beta-sheet such shealding is difficult.
     
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