Thus far Tevatron and possibly LHC has found no evidence of SUSY, and DM searches thus far null and void. Steinhardt had a paper showing that inflation is incompatible with higher dimensions. There are no experimental evidence for higher dimensions. Thus far proton decay and magnetic monopoles and cosmic strings have not been observed. It behooves us to ask whether 2 pillars of string theory, higher dimensions and SUSY are not be physical. Perhaps physical reality is really 4D with no SUSY. If string/M-theory is physically wrong (for example, neither higher dimensions nor SUSY nor d-branes are realized in nature), would Witten and other string theorists be remembered 20 years from now? if D-branes and SUSY are unphysical, are string theories' derivation of BH entropy and its conclusions about black hole information paradox valid? How many key results of string theory require SUSY and higher dimensions to be fundamental to nature, and what aspects of string theory can be useful to inform future physics research if the world is, in fact, 4D non-SUSY? for examples, KKLT and Ads/CFT have value? It's S-matrix and calculations of graviton scattering amplitudes? Topology changes? Application to heavy ion collisions? holography? T-duality and mirror symmetry? What would be salvageable for future physics if future physics is just 4D with no-SUSY, if string theory and its components like SUSY and extra dimensions are unrealized in nature? Has Witten, Suskind, Greene, Randall, etc string theory papers have value or dead end? Would there be a reason to continue string theory research if SUSY and extra dimensions are unphysical? Would it be scientifically responsible for Briane Greene and Michio Kaku to continue to promote string theory in the popular press to a lay audience if it has been shown that SUSY and extra dimensions are unphysical? Note: I'm not implying LQG (CDT, twistors, NCG etc) is correct, only that higher dimensions and SUSY (maybe GUT's) are unphysical.