This seriously made me laugh out loud!
But sysprog is right, I don't think Venus really has anything that would make it viable for people to live there. Autonomous mining maybe if, like you mentioned, there's something on the planet that's valuable. I imagine that if we ever become capable of...
You're probably already aware, but the Q Continuum from Star Trek is very similar to this. There's an episode (The Q and the Grey) where they talk about all of the Qs being bored with immortality. They don't talk about long term physical effects in the show, as they don't have bodies as we know...
At the time my story takes place, humans are in an evolutionary transition period. They have been able to modify DNA/genes so that people can have accessories, so to speak (communicator built into your arm, infrared sight, joints that can sustain falls from great heights, etc.), but very few...