I think you would do better if you would post specific questions rather than general ones.
If you really are given only that the line is given by
r= (a,b,c)+ t(A,B,C) and p= (p,q,r) (I've changed from (x,y,z) because I want to reserve that for an "unknown" point), then:
The line passes through the point (a,b,c) and has tangent vector (A,B,C). Geometrically, to find the point "symmetric" to (p,q,r) about the line, draw the perpendicular to the line from (p,q,r), and extend it beyond the line the same distance.
Algebraically, to find the perpendicular, let (x,y,z) be the point on the given line such that the line from (x,y,z) to (p,q,r) is perependicualr to the given line. The vector from (p,q,r) to (x,y,z) is (x-p,y-q,z-r). Since it is perpendicular to (A,B,C), their dot product is 0: A(x-p)+ B(y-q)+C(z-r)= 0.
Saying that (x,y,z) is on the line r= (a,b,c)+ t(A,B,C) means that, for some t, x= a+ tA, y= b+ tB, and z= c+ tC so that x-p= a-p+ tA, y- q= b-q+ tB, and z- r= c-r+ tC. The dot product becomes
A(a-p+ tA)+ B(b-q+ tB)+ C(c-r+ tC)= 0 or
A2t+ A(a-p)+ B2t+ B(b-q)+ C2t+C(c-r)= 0.
Then (A2+B2+C2)t= A(p-a)+B(q-b)+C(r-c) so
t= (A(p-a)+B(q-b)+C(r-c))/(A2+B2+C2).
You can use that t to find the point (x,y,z) and then the equation of the line through (x,y,z) and (p,q,r) as well as the distance between them. That's the information you need to calculate the symmetric point to (p,q,r).