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karthik3k
Mar22-04, 04:47 AM
I've got a protein produced by pathogens and i've got its sequence.
How would i know whether it can be a potential Drug target ....

iansmith
Mar22-04, 06:41 AM
You should do a BLASTP search at http://www.ncbi.nlm.nih.gov/BLAST/
This will give you homologue of you sequence and will give you a possible function including the target. The next step migth be to look for specific pattern at http://ca.expasy.org/tools/scanprosite/

Once you think you migth have a good target you can then do solid phase binding assays and affinity isolation.