Where Can I Find Full-Length Amino Acid Sequences?

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Discussion Overview

The discussion revolves around finding full-length amino acid sequences and the resources available for bioinformatics, particularly for beginners. Participants share their experiences and seek advice on navigating bioinformatics tools and terminology.

Discussion Character

  • Exploratory, Technical explanation, Conceptual clarification, Homework-related

Main Points Raised

  • One participant asks where to find full-length amino acid sequences, indicating a lack of bioinformatics background.
  • Another participant suggests using the NCBI website to search for protein or nucleotide sequences, mentioning the use of accession numbers for specific sequences.
  • A question is raised about whether the coding sequence (CDS) refers to the nucleotide sequence of mature mRNA or premature mRNA.
  • A participant clarifies that the CDS is the open reading frame (ORF) and refers to the premature form.
  • There is a request for simple resources or books to help beginners learn bioinformatics.
  • One participant mentions they are writing a tutorial about bioinformatics and plans to post it online.
  • Another participant shares their experience with bioinformatics and suggests that understanding the theory behind tools is essential for comprehension.
  • Language barriers are acknowledged, with participants expressing challenges in understanding bioinformatics terminology due to English not being their first language.

Areas of Agreement / Disagreement

Participants generally agree on the usefulness of the NCBI website for finding sequences, but there is some uncertainty regarding the definition of CDS. The discussion includes multiple perspectives on learning resources and language challenges, indicating a lack of consensus on the best approach for beginners.

Contextual Notes

Participants express varying levels of familiarity with bioinformatics, and there are references to specific terminology that may require further clarification. The discussion does not resolve the question about the nature of the CDS.

Who May Find This Useful

Individuals interested in bioinformatics, particularly beginners seeking guidance on finding amino acid sequences and understanding related concepts.

sotellme
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where can we get the full length of amino acid sequences? i have very little bioinformatic background so please the more you explain the better it would be :-p :biggrin:


thank you!
 
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go to the ncbi website (http://www.ncbi.nlm.nih.gov/) and do a search in their protein or nucleotide databanks. You type the protein or/and the organism that you want and can get acces to the protein or nucleotide sequence. If you have an accession number from a certain sequence (it usually giveen in scientific papers), you can find it using the search engine.
 
but the CDS is that the nucleotide sequence of the mature mRNA or premature mRNA?

BWT i am a beginner and really want to learn and use the tools in bioinformatic. do you know any place or books which is simple but quite useful?

thanks again!
 
the CDS is the ORF and it will be the premature form.

I am in the process of writing a tutorial about bioinformation.
 
iansmith said:
I am in the process of writing a tutorial about bioinformation.

hi!
is this your thesis or you have finished studying? you must know a lot about bioinformatic, then :cool: :smile:

the problem is English is not my language that is why a lot of words and explanations in the bioiformatic sites confuse me. i hardly understand what they are looking for :cry: do you have any advice you can afford me?

thanks!
 
I worked a lot with bioinformatics and took a graduate level course. I write the tutorial during my free time and it will be posted in the science article website.

As far as the language goes, english is not my first language either and sometimes to understand what they are asking for you have to know the theory behind tools.
 
okey! i will remember that :approve:



thanks!
 

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