Where does the body draw from to get energy first?

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Discussion Overview

The discussion centers on the sources of energy the body utilizes when glucose from food is depleted. It explores the order in which the body accesses various energy reserves, including glycogen, fats, and proteins, under different conditions such as exercise and starvation.

Discussion Character

  • Exploratory
  • Technical explanation
  • Debate/contested

Main Points Raised

  • Jacob questions where the body first draws energy from after glucose is depleted, mentioning vacuoles, glycogen reserves, and other potential energy stores.
  • Warren asserts that glycogen reserves are consumed first, with the liver converting glycogen to glucose for the bloodstream as blood glucose levels drop.
  • Another participant notes that glycogen is tapped into after all usable energy sources from food are exhausted, emphasizing that other macromolecules can also be metabolized.
  • A participant describes the order of energy usage during exercise as glucose, then glycogen, followed by fats, and highlights that during starvation, protein is used before fats, although fats become more prominent as starvation continues.
  • Nautica mentions that the very first source of energy is creatine phosphate, but only for a very brief period.
  • A later reply reiterates the order of energy sources during exercise and starvation, adding that lipids and amino acids can also be respired, with lipids yielding more energy than carbohydrates per mole.

Areas of Agreement / Disagreement

Participants express varying views on the order and sources of energy utilization, indicating that multiple competing perspectives remain without a clear consensus.

Contextual Notes

Some claims depend on specific conditions, such as exercise versus starvation, and there are unresolved details regarding the exact mechanisms and timing of energy source utilization.

wasteofo2
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Once you run out of usable glucose from food you've eaten, where is the first place the body turns to to get energy? If there is insufficient food in your body, do your individual cells first turn to their vacuoles for nourishment? Does your body dip into the glycogen reserves in your liver? Is there some other place spare energy is stored for easy acess?

Thanks,
Jacob
 
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AFAIK, the glycogen reserves are consumed first -- the liver begins converting the glycogen back to glucose and dumps it into the bloodstream as the blood glucose level falls. The liver does this automatically. Only if the liver failed would the cells have to turn to their own internal stores of energy.

- Warren
 
Glycogen reserves will be tapped into once you have run out of all usable energy sources from food, but not simply because you've run out of glucose. There are many other macromolecules in the food we eat that can be metabolized.
 
as far as i remember, it goes in the following order at least for muscles under exercise:

Glucose then Glycogen (as chroot said), then finally fats (from your fat stores)

But under starvation conditions, your body uses protein derived mostly from your muscles as fuel before fats at first, but begins to use more fats (as % of energy) as the starvation continues. Glycogen reserves are never depleted entirely even under these conditions, as its the preferred energy for the brain (although they can use ketone bodies derived from fat) and sole source for red blood cells.
 
Actually, the very first energy comes from creatine phosphate. But, only for a brief second or so.

Nautica
 
Jikx said:
as far as i remember, it goes in the following order at least for muscles under exercise:

Glucose then Glycogen (as chroot said), then finally fats (from your fat stores)

But under starvation conditions, your body uses protein derived mostly from your muscles as fuel before fats at first, but begins to use more fats (as % of energy) as the starvation continues. Glycogen reserves are never depleted entirely even under these conditions, as its the preferred energy for the brain (although they can use ketone bodies derived from fat) and sole source for red blood cells.
That sounds about right - lipids, amino acids (or more accurately keto acids after amino acids have be deaminated) can be respired too. In fact lipids yield more energy than carbohydrates, per mole.
 

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