When Do Viruses Die? The Lifespan of Common Viruses Outside of a Host

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Discussion Overview

The discussion revolves around the lifespan of viruses outside of a host, with a particular focus on HIV. Participants explore the conditions under which viruses become inactive or "die," the nature of viruses compared to prions, and the implications for virus transmission in various scenarios.

Discussion Character

  • Exploratory
  • Debate/contested
  • Technical explanation

Main Points Raised

  • Some participants suggest that a virus cannot "die" in the traditional sense, as it is not considered truly alive, referencing prions as a comparison.
  • Others clarify that viruses are distinct from prions, noting that viruses consist of proteins and nucleic acids.
  • It is proposed that viruses become inactive when damaged to the point they can no longer reproduce, with various factors such as white blood cells, chemical oxidation, and UV light mentioned as potential causes of inactivation.
  • Questions arise about the lifespan of HIV outside a host, with some participants referencing articles that suggest HIV does not last more than 20 minutes outside the body, while others express uncertainty and mention that some viruses can survive longer under certain conditions.
  • A scenario is presented regarding the potential transmission of HIV from a surface, raising questions about how long HIV remains in an active state without a host.
  • Some participants express skepticism about the longevity of viruses outside a host, while others reference the CDC's information on Hepatitis B, which can survive longer than a week outside the body.
  • There is a suggestion that environmental factors, such as UV radiation and heat, can affect virus longevity, and that viruses may last longer when protected from such conditions.

Areas of Agreement / Disagreement

Participants express differing views on the nature of viruses and their lifespan outside a host, with no consensus reached on the specifics of how long HIV or other viruses can survive in various conditions.

Contextual Notes

Limitations include varying definitions of "death" in relation to viruses, differing interpretations of lifespan based on environmental conditions, and the reliance on anecdotal evidence and external sources for claims about virus longevity.

Minorail
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I heard that virus attacks our body, but when does a virus die ?
E.g a HIV, do you know when it deis ? when is a white cell able to eat it ? or none of hiv's are eaten by any white cells ?
Thanku :wink:
 
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A virus is not a prion. A prion is a protein, a virus is a collection of proteins with nucleic acid carrying genetic material.
 
Viruses "die" (become inactivated...destroyed...whatever) when they are damaged enough such that they can no longer reproduce...whether it be through a white blood cell, chemical oxidation, UV light damage...whatever. The thing with HIV is that it attacks the body's immune system (rather than trying to hide from it/outpace it while attacking some other cells in the body).
 
Sorry for chiming in not at a right time, can someone tell me when will an HIV cell die ? :wink:
 
:wink:
it dies when it is damaged enough :wink:
 
Felixiass said:
can someone tell me when will an HIV cell die ?

what exactly is an "HIV cell"? Do you mean a cell that has been infected with HIV?
 
It is not incorrect at all.
 
So let's say a person with HIV bleeds all over the shopping mall floor. Someone wipes it up and cleans it with disinfectant, but the virus will still remain on the floor. Of course, the virus is inactive without a host to propagate in. Some unfortunate kid runs around and falls down, scraping his knee right where the HIV virus is. Will the kid get HIV?

How long will HIV stay for in a potentially active state when left alone with no host?
 
  • #10
I haven't heard of a virus lasting more than a day (as extreme cases) (something I read on Hep A/Hep C) without a host in non-ideal/everyday conditions. I read an article on HIV that stated it wouldn't last more than 20 minutes outside of host. I could be wrong, and there are definitely people with more information on the topic, but from what I have read, it doesn't last longer than that.

But if the blood was cleaned up, it is extremely unlikely that any transmission of HIV occurring.
 
  • #11
bross7 said:
I haven't heard of a virus lasting more than a day (as extreme cases) (something I read on Hep A/Hep C) without a host in non-ideal/everyday conditions. I read an article on HIV that stated it wouldn't last more than 20 minutes outside of host. I could be wrong, and there are definitely people with more information on the topic, but from what I have read, it doesn't last longer than that.

But if the blood was cleaned up, it is extremely unlikely that any transmission of HIV occurring.

The CDC says that Hepatitis B can survive more than a week outside of the body:

http://www.cdc.gov/ncidod/diseases/hepatitis/b/faqb.htm

I would not be surprised at all if there are viruses that can survive substantially longer. Afterall, we can consider viruses for all intents and purposes to be a big protein (ignoring the nucleic acids protected inside), and proteins can remain in a stable subunit configuration for a LONG time, especially if they were "meant" to be that way as most virus envelopes are.

Also, this is assuming the virus particles will be subject to UV radiation, heat, etc. If you take a virus, blot it on something like paper, put it in a plastic protector, it would last nearly indefinately.
 

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