Human Genome Help: Solving Time Calculation Question

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SUMMARY

The discussion revolves around calculating the time required for the human genome to diverge by 1%, given a non-overlapping mutation rate of 5000 mutations per day. With approximately 3 x 109 base pairs in the human genome, 1% equates to 3 x 107 mutations. The correct calculation indicates that it would take approximately 10 million years for this divergence to occur, rather than the incorrectly calculated 16 years. Key factors in this calculation include the mutation rate and the generation time of humans.

PREREQUISITES
  • Understanding of genetic mutation rates
  • Basic knowledge of human genome structure
  • Familiarity with evolutionary biology concepts
  • Ability to perform mathematical calculations involving large numbers
NEXT STEPS
  • Research "Human mutation rates and their implications" for deeper insights
  • Study "Evolutionary genetics and divergence times" to understand broader contexts
  • Learn about "Generation time in human reproduction" for accurate calculations
  • Explore "Mathematical modeling in evolutionary biology" for advanced techniques
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This discussion is beneficial for geneticists, evolutionary biologists, and students studying human genetics who seek to understand mutation rates and their long-term effects on genome divergence.

jesooka
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I am having trouble figuring out this question:

Assuming a non-overlapping mutation rate of 5000 mut/day. How long in years would it take for the human genome to diverge 1% (the genetic difference between humans and chimpanzees) from its current state?

If there are 3 x 10^9 pair in the human genome and 1% of this is 3 x 10^7 how do I figure out the amount of time to reach the 1%? I am stuck! I keep getting 16 years, I know that the number should be closer to 10 million years. Any starter tips or clues?
 
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You have to put in generation time :) how many times can a human reproduce in 16 years? And how did you get 5000 mut/day?
 

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