Is the Human Brain Still Evolving?

  • Context: Medical 
  • Thread starter Thread starter selfAdjoint
  • Start date Start date
  • Tags Tags
    Brain Human
Click For Summary

Discussion Overview

The discussion centers around the recent findings regarding the evolution of human brain size, specifically focusing on two genes that have reportedly developed rapidly under selection in recent history. The scope includes evolutionary biology and genetics, with references to specific time periods and implications for future research.

Discussion Character

  • Exploratory
  • Technical explanation
  • Debate/contested

Main Points Raised

  • Some participants highlight that two separate genes for brain size have been identified as having developed rapidly under selection, with one gene evolving since approximately 37,000 years ago and the other since about 5,300 years ago.
  • One participant questions the vectors of selection that led to the rapid development of these genes.
  • Another participant expresses enthusiasm about the implications of this research, suggesting it will lead to significant follow-up studies.
  • Several links to related articles and research papers are provided, including studies on ASPM and Microcephalin, which are associated with brain size determination.

Areas of Agreement / Disagreement

Participants do not reach a consensus on the specifics of the selection vectors or the broader implications of the findings, indicating that multiple viewpoints and uncertainties remain in the discussion.

Contextual Notes

Limitations include the lack of clarity on the mechanisms of selection and the definitions of terms used in the context of gene evolution and brain size.

selfAdjoint
Staff Emeritus
Gold Member
Dearly Missed
Messages
6,843
Reaction score
11
Breaking news; see this NY Times story. Two separate genes for brain size have been shown to have developed rapidly in recent times under selection, one since -37,000 (Cro-Magnon era), the other since only -5300 (neolithic, just before writing invented). The papers describing the research are in the current issue of Science.
 
Biology news on Phys.org
selfAdjoint said:
Breaking news; see this NY Times story. Two separate genes for brain size have been shown to have developed rapidly in recent times under selection, one since -37,000 (Cro-Magnon era), the other since only -5300 (neolithic, just before writing invented). The papers describing the research are in the current issue of Science.


great article! the work will have major repercussions and start a lot of other followup research I think

Here is a press release about this work from the Howard Hughes Medical Institute, and another HHMI link about Bruce Lahn


http://www.hhmi.org/news/lahn4.html

http://www.hhmi.org/research/investigators/lahn.html
 
some more links:

http://hmg.oxfordjournals.org/cgi/content/full/13/5/489
free download of complete Lahn ASPM article from Human Molecular Genetics
"Adaptive evolution of ASPM, a major determinant of cerebral cortical size in humans"

http://hmg.oxfordjournals.org/cgi/content/full/13/11/1139
free download of complete Lahn Microcephalin article from Human Molecular Genetics
"Reconstructing the evolutionary history of microcephalin, a gene controlling human brain size."

http://www.ncbi.nlm.nih.gov/entrez/...list_uids=15620360&itool=iconabstr&query_hl=5
abstract of Lahn article

http://www.ncbi.nlm.nih.gov/entrez/...d&dopt=Abstract&list_uids=16151009&query_hl=5
abstract of Lahn Microcephalin article in 9 Sept Science journal.

http://www.ncbi.nlm.nih.gov/entrez/...d&dopt=Abstract&list_uids=16151010&query_hl=5
abstract of Lahn ASPM article in 9 Sept Science
 

Similar threads

  • · Replies 1 ·
Replies
1
Views
2K
  • · Replies 1 ·
Replies
1
Views
2K
  • · Replies 2 ·
Replies
2
Views
3K
  • · Replies 6 ·
Replies
6
Views
6K
  • · Replies 1 ·
Replies
1
Views
3K
  • · Replies 1 ·
Replies
1
Views
3K
  • · Replies 26 ·
Replies
26
Views
8K
  • · Replies 5 ·
Replies
5
Views
5K
Replies
14
Views
8K
  • · Replies 1 ·
Replies
1
Views
2K