 Quote by phyzguy
Of course what you say is true, but how is the connection to relativity any different? This was the original question.
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I answered it above. There is no mass difference between the reactants and products in combustion because the energy is all stored in covalent bonds which are completely a electromagnetic phenomenon, whereas there is mass loss in a nuclear reaction because the the binding energy of the mother nucleus is greater than the sum of the daughter nuclei due to the mass energy equivalence described in general relativity.