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Difference Between GABA A and GABA B?

by powerof1004
Tags: difference, gaba
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powerof1004
#1
Feb29-12, 02:20 AM
P: 9
Difference Between GABA A and GABA B?
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Pythagorean
#2
Feb29-12, 03:42 AM
PF Gold
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P: 4,287
In what sense?

At the molecular level, A receptors are Cl- ion channels, B receptors activate metabolic pathways. So A directly affects electrophysical properties, B affects molecular network dynamics through G protein cascades (which shut down the neuron's ion reactivity and down-regulates adenyl cyclase).


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