Diseases related to chemokines ?

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Discussion Overview

The discussion revolves around the relationship between chemokines and various diseases, as well as the exploration of research methodologies involving chemokines, particularly in the context of project design and metabolic pathways.

Discussion Character

  • Exploratory
  • Technical explanation
  • Homework-related

Main Points Raised

  • One participant inquires about diseases related to chemokines, noting difficulty in finding information on the KEGG database.
  • Another participant suggests articles that may provide insights into chemokines and their association with diseases such as Alzheimer's and autoimmune diseases.
  • A participant expresses interest in designing a project involving docking studies of chemokines and running molecular dynamics simulations to analyze energy profiles.
  • Another participant recommends a specific paper to assist in getting started with the project.
  • A participant mentions having limited access to papers from a journal but considers it a good starting point and seeks information on metabolic pathways related to chemokines, expressing confusion about their absence in the KEGG database.

Areas of Agreement / Disagreement

Participants do not appear to reach a consensus on the availability of information regarding chemokines in databases or the specific diseases they are associated with. Multiple viewpoints regarding research directions and resource availability are present.

Contextual Notes

Participants express uncertainty about the availability of chemokine-related information in databases like KEGG and the specific methodologies for their research projects. There are also limitations regarding access to academic papers.

Who May Find This Useful

Researchers and students interested in chemokines, disease mechanisms, and molecular dynamics simulations may find this discussion relevant.

karthik3k
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What are the diseases realated to chemokines ??
I couldn't find anything about it on KEGG database!
 
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Actually i got to design a project.
Since iam interested in Chemokines...
I wanted to do something like...
Docking chemokine...with ...
and running a MD (with AMBER/GROMACS) to check the Energy profiles ? of all clusters ..


Any idea How and what to start with ??
 
You should check the following paper

http://www.biophysj.org/cgi/content/full/83/6/3012

this paper should help you getting started
 
Last edited by a moderator:
Thanks
I got only single paper from that journal. But that's a good start.
Where can i get about the information in metabolic pathways?
I couldn't find Chemokines in KEGG or may be i didnt know where to find in that.
 

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