What do you mean by "observed"? Do you mean observed on a human timescale?
If that's what you mean, the answer is probably difficult, but if that's what you mean, why would you put such a constraint on evolution? That constraint is simply inappropriate and unnecessary in science. There are plenty of phenomena that we observe in science that are too fast (time dilation - nanosecond accuracy required), too slow (most of geology/astronomy), too small (cellular biology, materials science), too dim (astronomy), in the wrong frequency of light (astronomy, radio communications), etc. for us to observe in human timescales/with human sensory organs. Science long ago started to progress beyond what humans could discover with our senses - centuries ago.