Smells come from the binding of airborne chemicals with odor receptors.
Cell Mol Life Sci. 2004 Feb;61(4):456-69.
Olfactory receptors.
Gaillard I, Rouquier S, Giorgi D.
IGH, CNRS UPR1142, rue de la Cardonille, 34396 Montpellier, France. gaillard@ensam.inra.fr
Olfaction is an ancient sensory system allowing an organism to detect chemicals in its environment. The first step in odor transduction is mediated by binding odorants to olfactory receptors (ORs) which belong to the heptahelical G-protein-coupled receptor (GPCR) superfamily. Mammalian ORs are disposed in clusters on virtually all chromosomes. They are encoded by the largest multigene family (approximately 1000 members) in the genome of mammals and Caenorhabditis elegans, whereas Drosophila contains only 60 genes. Each OR specifically recognizes a set of odorous molecules that share common molecular features. In mammals, signal transduces through the G-protein-dependent signal pathway in the olfactory sensory neurons that synapse ultimately in the glomeruli of the olfactory bulb, and is finally processed in higher brain structures. The expression of a given OR conditions neuron and glomerulus choices. To date, the processes which monitor OR expression and axon wiring have emerged but are not completely elucidated.
Publication Types:
Review
Review, Tutorial
PMID: 14999405 [PubMed - indexed for MEDLINE]
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It's kind of late for me here now, so I'm not going to look up any more articles tonight, but I recall from a seminar I attended that odor signals are also context-dependent. In other words, the same odorant chemicals are present in both microwave popcorn and vomit, or possibly it's the same receptors for similar chemicals (I will need to double check the details) , so if you hear the popcorn popping, you smell popcorn, and if you see vomit, you smell vomit, but if you don't have proper context cues, your own perceptions could tell you it's either. The woman who presented the seminar was French and used the microwave popcorn example (first time she smelled it, she thought it smelled like vomit), along with the example of stinky French cheese that she loves and her students think smells like stinky feet.
Vance, I don't remember seeing your post about smells. Maybe I missed it, or maybe you asked a slightly different question I couldn't answer.