Hemoglobin S Trait

Soaring Crane

If a person is a carrier for sickle cell disease or has hemoglobin AS, then does this mean that the carrier is not affected by hemoglobinopathy? (He/she is normal/healthy?)

Thank you.

epenguin

Yes, or healthy enough. And surely you have or will come across the story of why they are HEALTHIER than people with only A in certain environments, explaining why S became as common as it did?

Soaring Crane

Thanks, epenguin. Yes, they are protected from malaria?

epenguin

That's right. Suggesting that 'healthy' is often only relative to an environment. (And sometimes to other genetic background).
I can't say whether they may not have some slight disadvantage away from the malarial environments.