Recent content by Quickdry135

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    Undergrad Are atoms 'perpetual machines'?

    As I understand it, electrons around a nucleus are more like a probability cloud. If I'm remembering correctly, at that level it starts falling into quantum mechanics. They don't really orbit on specific planes like planets around a sun, but rather are more likely found in one position rather...
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    Undergrad Cantilever Deflection: Equation for Uniform Load

    It's been a while since I've studied mechanics. Would someone remind me as to the equation for the deflection of a cantilever beam with a uniformly distributed load on only a part of the beam? I remember the equation for a load on the entire beam is (wL^4)/(8EI) thanks.
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    What is the effect of temperature on ligand integrin dimerization?

    thanks, for part A, I was thinking that I could use Ka=[X]/[.5*initial complex-x]^2 to find X which would be the dimer concentration. Then I could use that over the initial complex concentration which is given to find the fraction. Would this work?
  4. Q

    What is the effect of temperature on ligand integrin dimerization?

    Homework Statement 3 different RGD-containing ligands (including Integrilin) are used to form receptor-ligand complexes, and measured dimerization of ligand-bound receptors as a fuction of temperature in the range 20-40C using a variety of methods. The 3 ligands are cHArGd, cRGD, and...
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    Calculating Probability of Ligand-Protein Binding at Equilibrium

    Ok thanks anyway, I know there's a probability equation pertaining to this in physical chemistry, but for the life of me I can't remember it or find it in my book.
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    What Are the Oxidation Numbers in Zn(NO3)2?

    NO3 should carry it's original Oxidation numbers when becoming Zn(NO3)2 since it's splits from H which carries a +1 charge. That would make NO3- (a -1 oxidation number for the entire ion since you already stated that N=+5 and O=-2 per molecule). Combining 2 NO3- groups with Zn would give Zn an...
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    Calculating Probability of Ligand-Protein Binding at Equilibrium

    The scatchard equation is (r/c) = Ka*n - Ka*r, where r is the ratio of the concentration of bound ligand to total available binding sites, c is the concentration of free ligand, Ka is the association constant, and n is the number of binding sites per protein, right? So through this I could find...
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    Calculating Probability of Ligand-Protein Binding at Equilibrium

    Homework Statement A monovalent ligand binds to a protein with six in independent, identical binding sites. What is the probability that a given protein molecule is bound by at least five ligand molecules at equilibrium if K^{\mu}_{D} = 1nM and L_{0}=2nM (constant)? Homework Equations...
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    Isothermal titration calorimetry

    never mind, I think i figured it out using the van't hoff equation to find delta H at 37C since I can find the different Kds and am given the different temperatures.
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    Isothermal titration calorimetry

    Homework Statement Using isothermal titration calorimetry, you calculate \DeltaH^{o}_{bind} (= -5000 cal/mol) for a protein-ligand binding reaction at 25°C. You then perform a separate assay in which you measure equilibrium ligand binding at two different temperatures: L_{0} (nM)...