Yes, most compressors (pressure pumps) can be used as a vacuum pump simply by choosing how you apply the inlet and discharge of the pump. With an open inlet to atmosphere and the discharge piped off, it acts as a compressor pumping up the pressure in the discharge manifold. If the inlet is piped off and the discharge is open to atmosphere then it acts as a vacuum pump reducing the pressure inside the inlet manifold. The type of seals and cooling methods designed for the particular machine will help predict how much positive or negative pressure the pump can produce and for how long.