Did Biosphere 2 discoveries inform design of the ISS or other manned spaceflight?

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Ganesh Ujwal
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My Actual Question: Did Biosphere 2 make any discoveries later used on manned space flight?

Biosphere 2 operated as a closed entity for study of closed ecological systems for stints between 1991 to 1994. Given that the ISS has been continuously inhabited from 2000 to the present day, it seems like any lessons learned from Biosphere 2 would have been timely and relevant.

Was there even a single discovery or clearly identifiable scientific product that resulted from Biosphere 2 and was later used for the ISS or other manned spaceflight?
 
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I visited the biosphere two and spoke with a researcher from Columbia about some of the plants they had there. I've found no evidence for identifiable scientific product(s) later used by the ISS and/or other manned spaceflight. However, researchers of biosphere two found the original crew's lowered blood pressure, blood cholesterol, and enhancement of there immune systems to be caused by Roy Walford's low calorie restriction diet (Walford, R., Mock D, Verdery R, MacCallum T, Calorie Restriction in Biosphere 2 Alterations in Physiologic, Hematologic, Hormonal, and Biochemical Parameters in Humans Restricted for a 2-Year Period). Perhaps, this could be interpreted as a model for outer space cuisine for astronauts. Probably not though. Currently, researchers at biosphere two study different biomes and there interactions.
 
Ganesh Ujwal said:
Was there even a single discovery or clearly identifiable scientific product that resulted from Biosphere 2 and was later used for the ISS or other manned spaceflight?

The main lesson to be learned from Biosphere 2 is not to favor publicity over science. I don't know if this was used for ISS or other manned spaceflight but I hope it will be considered for any major project in space or on Earth.