I read somewhere the dictum that 'nothing can be done without at least a material base' ; the way the term matter was employed in this text implied that vacuum, 'empty' space, was to be viewed as matter-less. This would mean that in empty space, nothing at all can be done. This leads to an important question: Can empty space be made into matter/energy? And vice versa? In other words, can something occur like : A + vacuum -> B + C , where the matter/energy of B and C does not equate with that of A. The vice versa is even more important: is there a way in which matter/energy 'deteriorates' and becomes something like empty space? Thanks.