Understanding Integral and Peripheral Proteins: Biology Q&A

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SUMMARY

The discussion focuses on the classification of membrane proteins, specifically integral and peripheral proteins, and the mechanisms of transport across the plasma membrane. Integral proteins, such as the glucose transporter and sodium-potassium pump, span both sides of the membrane, while peripheral proteins are associated with only one side. The ion channel is classified as a peripheral protein. Additionally, the glucose transporter GLUT-1 and sodium-potassium pump are involved in active transport, while the ion channel facilitates diffusion.

PREREQUISITES
  • Understanding of integral and peripheral membrane proteins
  • Knowledge of transport mechanisms: facilitated diffusion and active transport
  • Familiarity with protein functions in cellular membranes
  • Basic concepts of concentration gradients in biology
NEXT STEPS
  • Research the structure and function of integral membrane proteins
  • Learn about the mechanisms of facilitated diffusion and active transport
  • Study the role of the sodium-potassium pump in cellular homeostasis
  • Explore the differences between various types of ion channels
USEFUL FOR

Biology students, educators, and professionals in the fields of cellular biology and biochemistry who seek to deepen their understanding of membrane protein functions and transport mechanisms.

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Proteins associated with the plasma membrane can be classified as either integral membrane proteins or peripheral membrane proteins. For the following types of proteins, please specify whether they would be integral or peripheral.
Glucose transporter
Sodium-potassium pump
Ion channel

-I think that peripheral membranes are only on one side of the membrane whereas integral proteins are on both sides of the membrane. Therefore, I thought that glucose transporter was integral, sodium potassium was integral, and ion channel was peripheral. What am I doing wrong?

MY NEXT QUESTION:
Transport of large or hydrophilic molecules across the plasma membrane can occur via facilitated diffusion or via active transport. For the following types of proteins, please indicated which type of transport is involved.

Ion channel
Glucose transporter GLUT-1
Sodium-potassium pump

Active transport is when molecules can cross against the concentration gradient whereas faclitated diffusion can't go across the concentration gradient. So this is what I did: for ion channel, I said faclitated diffusion, glucose transporter is active transport, and sodium potassium pump is active transport. Where am I going wrong?

Any help would be appreciated! Thanks.
 
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