Yang-Mills theories are non-Abelian generalizations of Maxwell's theory. You start with a gauge group just like in Maxwell's theory, but instead of being a collection of numbers, it is a collection of matrices.
Small gauge transformation are defined with respect to group elements continuously connected with the unit matrix, as with a Taylor expansion of the exponential function about the unit matrix. If they are not `connected' to the unit matrix then they correspond to what are called large gauge transformations. Examples of `disconnected' gauge transformations occur with a non-Abelian gauge theory where you have a topologically non-trivial configuration space. Such disconnected gauge transformations do not occur with Abelian gauge theory - i.e. Maxwell's theory.
You want to look at the WKB approximation and "Instantons" (for a start) which can be used to probe the nonperturbative realm of gauge theories.
You can have a look at chapter 16 of "Quantum Field Theory" by Michio Kaku.