What Are Unusual DNA Structures Like Hoogsteen Pairs and Hairpin Structures?

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SUMMARY

This discussion focuses on unusual DNA structures, specifically Hoogsteen pairs and hairpin structures, as well as related concepts like mirror repeats and g-tetraplexes. Participants engaged in a fill-in-the-blank exercise to identify various DNA structures based on specific definitions and characteristics. Key terms included duplex DNA, inverted repeats, and cruciform structures. The discussion emphasized the importance of understanding the properties and formation of these unique DNA configurations.

PREREQUISITES
  • Understanding of DNA structure and base pairing
  • Familiarity with terms like mirror repeat and inverted repeat
  • Knowledge of four-stranded DNA structures such as g-tetraplex
  • Basic concepts of DNA folding and hydrogen bonding interactions
NEXT STEPS
  • Research the properties and formation mechanisms of Hoogsteen pairs
  • Study the characteristics and biological significance of hairpin structures
  • Learn about the formation and implications of g-tetraplex DNA
  • Explore the concept of triplex DNA and its role in genetic regulation
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Students and researchers in molecular biology, geneticists, and anyone interested in advanced DNA structures and their implications in genetics and biochemistry.

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i have to fill in the blanks for the following questions using the following choices (some will be used once, others more than once, and others not at all) : z-dna, cruciform structure, mirror repeat, hairpin structure, g-tetraplex, triplex dna, hoogsteen pairs, a-dna, duplex dna, inverted repeat.

1. A(n) ____ does not have complementary sequence on the same strand.

2. a(n) _________ is self-complementary.

3. a sequence, such as a palindrome, that can be rotated 180 degrees horizontally and 180 vertically in order to superimpose a sequence repeat on the other sequence is a(n):__________

4. a four-stranded, right-handed helix formed by a dna segment containing a high proportion of guanine residues is known as a(n)_______________

5. in a(n) _____________, interstrand hydrogen bonds break and intrastrand hydrogen bonds form.

6. an inverted repeat that occurs within a single dna strand is a(n)_________

7. the sequence -GTGAG...CTCAC-
-CACTC...GAGTG- is a(n)_____________ and has the potential to form a(n)______________.

8. _____________ can form when a polynucleotide strand forms ___________ with functional groups in the major groove of a homopurine-homopyrimidine duplex that can contain a mirror repeat.

9. a single dna strand with the sequence-ATATG...CATAT-can form a(n) ______________.

the hint given is a mirror repeat has symmetry such that folding the sequence back onto itself superimposes the bases. however, then folding the the sequence onto the opposite strand does not superimpose the bases. consider whether a mirror repeat has a superimposable sequence in the complementary strand.

thank you so much for your help!





My answers were the following but some are incorrect:
1. mirror repeat
2. duplex dna
3. mirror repeat
4. g-tetraplex
5. hairpin structure
6. mirror repeat
7. inverted, cruciform structure
8. triplex dna, hoogsteen pairs
9. hairpin structure
 
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People here won't just answer your questions for you. How can we help you better understand the material? What specific things don't you understand? Which parts are you having trouble with?
 
I checked my answers and I do not undersand why some of them are incorrect.
 

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