Can Experts in Slime Mold Proteins Make Hybrid Proteins?

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Discussion Overview

The discussion revolves around the specialization in slime mold proteins, the potential for creating hybrid proteins, and the implications of such modifications on protein properties and functions. It includes inquiries about terminology, the effects of amino acid changes, and the conditions under which hybrid proteins may retain or lose functionality.

Discussion Character

  • Exploratory
  • Technical explanation
  • Conceptual clarification
  • Debate/contested

Main Points Raised

  • Some participants inquire about the terminology used for specialists in slime mold proteins and the relevant fields of study.
  • There is a suggestion that hybrid proteins can be created, with a reference to GFP as an example.
  • Questions are raised regarding the likelihood that hybridization will alter protein properties, with a request for clarification on what "properties" entails.
  • One participant explains that proteins are chains of amino acids and that even a single amino acid change can significantly affect function.
  • Another participant seeks clarification on whether "properties" always includes actions and under what circumstances hybrid proteins might retain or lose their functions.
  • A response indicates that changes to the active site or significant alterations in size can lead to loss of function in hybrid proteins.
  • There is a request for more specificity regarding the topic of discussion, indicating a need for further details about the protein or gene question being posed.

Areas of Agreement / Disagreement

Participants express varying degrees of uncertainty regarding the effects of hybridization on protein properties and functions. There is no consensus on the specific conditions that would lead to changes in action or properties.

Contextual Notes

Limitations include the lack of detailed definitions for terms like "properties" and "actions," as well as the absence of specific examples or contexts that could clarify the discussion further.

Who May Find This Useful

Researchers or students interested in protein biochemistry, genetic engineering, or the study of slime molds may find this discussion relevant.

NeedBioInfo
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What would people who specialize in slime mold/slime mold proteins be called? What field would they be in? Thanks

I guess another thing I want to know is, would it be possible to make hybrid proteins?
 
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NeedBioInfo said:
What would people who specialize in slime mold/slime mold proteins be called? What field would they be in? Thanks
I don't think there is a special name. The field would depend on what kind of research they are engaging themselves in. To find articles relevant to slime molds, look on www.pubmed.com.
I guess another thing I want to know is, would it be possible to make hybrid proteins?
Yes, that's possible (think GFP). Be aware that the properties of a protein are likely to change when you make a hybrid.
 
What are the odds that the properties of a protein will change when it becomes a hybrid, what affects that, etc?

Thanks

And by properties do you mean actions?

Thanks
 
proteins are just chains of amino acids that fold into structures which leads to different functions. two proteins can differ by one one amino acid, and their functions can change dramatically if one amino acid is altered.

properties and actions both.
 
Um, when you're using "properties" in this context, are you using it in a way which always includes actions? I mean, what are you using properties to refer to?

Making a hybrid protein out of a protein wouldn't always change the action of the protein right? Could somebody give me some info on the circumstances where it would and wouldn't?

(Sorry, edited post)

Thanks
 
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The action changes when you change the protein in such a way that it can not act anymore. When you change a single aminoacid in the active site, the whole function of the protein will be lost. If the protein needs to translocate from the cytoplasm and the nucleus and you make a really large hybrid, it can not translocate anymore. You can think of other situations.
 
Hey Needbioinfo, can you be more specific as to what topic this is about?

is this a protein question or does it have to do with any specific thing you are doing.
I already explained the protein thing, do you want more details?
 
It's a protein/gene question about some specific things...do you know when you'll be back? Anyways thanks
 

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