Register to reply

Amide coupling reagents

by gravenewworld
Tags: amide, coupling, reagents
Share this thread:
Aug4-04, 07:04 AM
P: 1,410
I'm trying to find a coupling reagent for reacting an amine with a carboxylic acid. Currently I am using TBTU with fenchyl amine hydrochloride, but the amine seems not to want to react witht the carboxylic acid. Are there some better coupling reagents than TBTU out there that anyone knows of?
Phys.Org News Partner Chemistry news on
Video: How did life on Earth begin?
Now you can turn your inkjet printer into a chemistry lab and use it to diagnose diabetes
Advanced molecular 'sieves' could be used for carbon capture
Aug4-04, 10:51 AM
Sci Advisor
P: 284
Here's a whole list of them:

They've got the CAS numbers listed there so you can cross-reference them to a chemical catalog.

I would say the ones I have seen the most often are CDI, HOBT, DCC, and EDCI.
Aug4-04, 11:18 AM
P: 1,410
awesome thanks!

Aug5-04, 12:07 AM
P: 210
Amide coupling reagents

I don't have anything to contribute to this thread, however you two dudes seem into this whole chemistry game.

Perhaps you'd be interested in the following forum:

Register to reply

Related Discussions
Limiting and excess reagents Biology, Chemistry & Other Homework 3
ALuminum reactions with reagents Chemistry 6
Grignard Reagents Biology, Chemistry & Other Homework 0
Chemistry - Limiting reagents Biology, Chemistry & Other Homework 4
Synthesis of a nitrile from an amide Chemistry 4