 Quote by ladykrimson
1. The weightlessness is one of the big barriers. I have seen some suggestions to spin the ship on the way to Mars, in order to simulate gravity for the crew. It seems like a sound method to me and fairly easy to enact. What are the complications or problems for this method?
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The objection to this one is that in order to get an appreciable gravity, you need to either have a very large object or make it rotating very quickly. The problems with either of these are quite obvious, so it's actually not that easy to enact this one.
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2. Necessary supplies will weigh the ship down, making it difficult to launch from Earth. It has been suggested to build a spacecraft in orbit and then send supplies up with other manned missions. When the spacecraft is built and supplied, the astronauts could then launch in a smaller craft and dock with the larger craft. Aside from the cost, what are complications or problems with this suggestion?
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Nothing's wrong with it. A mission to mars would take a long time, and likely require a spacecraft much larger than we've currently seen. It's therefore necessary that it be assembled in orbit, much in a similar way the ISS has been. It's much cheaper to do it in this piecewise fashion than to launch the whole thing in one go.
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3. I have searched many places, but I can't find an answer to this. Have humans discovered a way to generate an electro-magnetic shield? If so, could this be applied to the ship with the manned mission to Mars? I realize that it wouldn't be as powerful as Earth's, but could it, at least, provide some protection?
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Well, lead makes a pretty good EM shield. Or any metal, really. The issue is just one of weight and practicality. As far as trying to generate an E-M field like the Earth's, that's much more difficult. Likely, any device powerful enough to provide significant protection would also wreck serious havoc on the spacecraft itself!
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4. Enough fuel to get to Mars and then return would weigh down the ship. Is it possible to fuel the ship in orbit with the necessary amount of fuel? Why don't we have some type of fueling station already in orbit? Wouldn't that be an economical investment if humans intend to explore space further or even sending out more probes?
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Like I said in response to 2, you pretty much must construct the craft in orbit. At any rate, you still have to ship the fuel to LEO or some similar orbit, which is still a costly endeavor. So unless you could manufacture the fuel already in space (and I know of no practical way to do so), it's not that much better.
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5. Just like on the moon, why are we not sending some kind of probe in advance of the mission to collect some Martian samples and return them to Earth? That way, NASA could get an idea of what it takes to land a craft safely on Mars and launch from Mars safely.
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The moon is very very much closer than mars. Not only that, it's also much less massive. Not to imply that mars is huge, but it takes significantly more thrust to lift off of Mars than it does to lift off of the moon. So to get back is a much bigger undertaking. It makes good sense to perhaps try to get a craft back from mars from a learning perspective, but economically you probably more than double the cost of the mission. We already know how to land on mars, and we've taken off the moon, so I would think it's just a problem of scaling in taking off.