Blood groups and transfusions .

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SUMMARY

This discussion centers on the compatibility of blood groups during transfusions, specifically addressing the phenomenon of agglutination. When type A blood is transfused to a type B recipient, agglutination occurs due to the presence of anti-A antibodies in the recipient. However, individuals with AB blood type are considered universal recipients because they lack anti-A and anti-B antibodies, allowing them to receive A blood without significant immune response. The discussion highlights that while AB recipients may receive A blood, it is preferable for them to receive AB blood to minimize any potential reactions.

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  • Knowledge of immunology, particularly antibody-antigen interactions.
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Cheman
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Blood groups and transfusions...

I have learned that when you transfuse the wrong blood to a recipient whose antibodies work against the donated blood that agglutination occurs. eg - if you transfuse A blood to a B person, since the B person will possesses anti-A antibodies which will cause agglutination, but an AB person can receive A blood because their blood contains no antibodies.

But surely the donated A blood would contain some anti-B antibodies which would cause agglutination of the red blood cells in the AB person? Why does this not happen? ie - we still call the AB a universal recipient.

Thanks.
 
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Cheman said:
But surely the donated A blood would contain some anti-B antibodies which would cause agglutination of the red blood cells in the AB person? Why does this not happen? ie - we still call the AB a universal recipient.

It does happen on some occasion but people of group AB will preferentially receive blood from an AB person rather than anyone else.

You also have to note the amount of anti-B antibodies in the transfused blood might be not sufficient to cause a significant immune responce in certain individuals.
 
Please could people elaborate?
 

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